Toxin induced cardiomyopathy
WebToxic cardiomyopathies Examples of toxic cardiomyopathies of various characteristics are presented. Daunomycin and doxorubicin, antineoplastic drugs, cause multifocal cardiomyopathies and intractable heart failure by cardiotoxic mechanisms; these effects are delayed and related to the cumulative dose. Cobalt caused diffus … WebApr 2, 2024 · Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle that makes it harder for the heart to pump blood to the rest of the body. Cardiomyopathy can lead to heart failure. The main types of …
Toxin induced cardiomyopathy
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WebDifferent mechanisms for cardiac injury due to methamphetamine have been proposed which include catecholamine excess, coronary vasospasm and ischaemia, increase in reactive oxygen species, mitochondrial injury, changes in myocardial metabolism, and direct toxic effects 3.Methamphetamine use is known to cause acute and chronic … WebMar 1, 2011 · Discussion. Echocardiographic findings of HCQ cardiomyopathy are variable, ranging from increased ventricular wall thickness with or without dilatation and systolic or diastolic dysfunction and can mimic other causes of myocardial dysfunction in SLE patients such as myocarditis, amyloidosis, ischemic heart disease, other toxic drugs (eg, …
WebAug 8, 2024 · Alcohol-induced toxicity leads to non-ischemic dilated cardiomyopathy characterized by loss of contractile function and dilatation of myocardial ventricles. These findings are coupled with a clinical history … WebMar 1, 2024 · T-2 toxin, A trichothecenes mycotoxin, is immunotoxic to animals and humans.Although it is highly cardiotoxic, the pathogenesis of cardiomyopathy caused by T-2 toxin is not entirely clear. Hence, in our research, cardiomyopathy was induced by a single injection of T-2 mycotoxin (0.23 mg/kg s.c., 1 LD 50) to Wistar rats.The cardiac tissue was …
WebCardiomyopathy, Dilated / chemically induced*. Cardiomyopathy, Dilated / diagnostic imaging*. Cardiomyopathy, Dilated / drug therapy. Cocaine / adverse effects*. Cocaine … WebConclusions: The mechanisms behind toxic cardiomyopathy are complex and multifactorial but include interference with myocardial cell bioenergetics and intracellular calcium …
Webevasive diagnosis of HCQ-induced cardiomyopathy.4 Learning points Cardiomyopathy is a potentially reversible adverse effect of hydroxychloroquine (HCQ) therapy. Due to its similarity with other lysosomal storage disorders as well as limited number of cases, the diagnosis remains under-reported and underdiagnosed.
WebDec 14, 2024 · The cardiotoxicity of other antineoplastic drugs, including anthracyclines and taxanes, management of heart failure, and clinical use of trastuzumab and other HER2 … o2 free trialWebThese toxic substances can cause oxidative stress, inflammation, and damage to the cardiomyocytes, leading to the development of ACM. [3] Additionally, chronic alcohol consumption can lead to deficiencies in essential vitamins and minerals, such as thiamine, magnesium, and selenium, which are important for the proper functioning of the heart [4]. mahe airport loungeWebOne of the commonest presentations of anthracycline-induced cardiomyopathy is in women treated for metastatic breast cancer. Direct toxic damage to the myocardium usually affects the inter-ventricular septum first. ... Mitochondrial dysfunction appears to play a pivotal role in patients with toxin- and tachycardia-induced heart failure. In ... o2 free samsung earbuds