WebSep 15, 2011 · Human evaluations of photoirritation or photoallergy potential are available to confirm the absence of such effects. Long-term photo co-carcinogenicity testing has been evaluated using the SKH1 albino hairless mouse model. This is often preceded or replaced by photogenotoxicity testing; for example, in vitro photo-Ames, photoclastogenicity ... WebJul 14, 2011 · Photochemical genotoxicity was evaluated in human keratinocyte NCTC2544 cells. The cells were pre-treated with photogenotoxic or pseudophotoclastogenic chemicals and irradiated with a...
The rise and fall of photomutagenesis - ScienceDirect
WebApr 1, 2013 · The observations of pseudo-photoclastogenicity [32], [33], [39] for non-absorbing chemicals carried much weight in the deliberations. The revision of ICH S2 … WebJun 11, 2024 · The results showed the 3T3 NRU phototoxicity assay was poorly predictive of photosafety in vivo . In terms of photogenotoxicity, the EFPIA survey was even more startling. Again, the majority of compounds were positive for mammalian photoclastogenicity (20/27) or bacterial photomutagenicity (4/6), but this was irrespective … how to scan document to file windows 10
Clastogenicity, photo-clastogenicity or pseudo-photo-clastogenicity …
WebNov 1, 2010 · The photoclastogenicity assays were performed as described by Dufour et al. (2006). Briefly, CHO-Wbl cells were cultured in McCoy’s 5A medium containing 10% (v/v) … WebFind all the synonyms and alternative words for photogenicity at Synonyms.com, the largest free online thesaurus, antonyms, definitions and translations resource on the web. WebSep 1, 1996 · The oxygen radical scavengers catalase, superoxide dismutase and N, N'-dimethylurea modulated the photoclastogenicity and phototoxicity but had no influence on the effects in the Comet and Ames tests. It thus appears that different kinds of mechanism are responsible for toxicity and clastogenicity on the one side and DNA breakage and … north mercer