Phospho-slp-76 ser376
WebSLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on multiple residues, resulting in the protein being … WebMouse phospho-SLP-76 (Ser376) control lysate HTRF® This lysate is a component of the mouse phospho-SLP-76 (Ser376) kit. It may be used as a residue specific positive control for mouse SLP-76 phosphorylation. See more Size Cat. number selected : - Quantity Request for quotation Prices may differ between countries.
Phospho-slp-76 ser376
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WebSLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus … WebNo-wash kit for detection and quantitation of phospho-SLP-76 in cells using AlphaLISA SureFire technology. We are now two standalone organizations Life Sciences & …
WebSLP-76 (Phospho-Ser376) Rabbit Polyclonal Antibody Product Code AMS.BT-AP04769-100ul Skip to the end of the images gallery Skip to the beginning of the images gallery $230.00 Qty Add to Cart Request Quote for Bulk Pricing Order Support T: +1 (617) 945 5033 T: +1 (800) 987 0985 (toll free) F: +1 (617) 945 8218 Email: [email protected] WebMay 2024 - Sep 20241 year 5 months. 1250 S Collegeville Rd, Collegeville, PA 19426. • Demonstrated the in vivo efficacy of various GSK’s proprietary small molecules for their …
WebFeb 27, 2024 · Image: ELISA detection of phospho-SLP-76 (Ser376) using a FastScan™ sandwich ELISA kit from Cell Signaling Technology. Treatment efficacy is supported by Western blot analysis. Consider using automation WebJan 20, 2024 · We report here that SLP76-S376A-expressing mice exhibit normal thymocyte development and no detectable phenotypic alterations in mature T cell subsets or other lymphoid and myeloid cell lineages. Biochemical analyses revealed that mutant T cells were hypersensitive to TCR stimulation.
WebPhospho-SLP-76 (Ser376) (E3G9U) XP ® Rabbit mAb recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. Non-specific staining was observed in …
WebSLP-76 phosphorylated at Ser376 and another that recognizes an invariant epitope of SLP-76. ... Eu-Ab1 and FR-Ab2 (5 µL) for detection of phospho-SLP-76 (S376). • The plate was incubated at RT for . 18 hours. and the TR-FRET signal . was recorded at 665 and 615 nm (EnVision®; lamp excitation). grain-by-products definitonWebThe Mouse Total SLP-76 cellular assay kit is designed to monitor the expression level of SLP-76, whether phosphorylated or unphosphorylated. It is compatible with our Mouse phospho-SLP-76 (Ser376) kit, and enables the analysis of phosphorylated and total proteins from a single sample for better readouts of T-lymphocyte activation. Benefits china lights milwaukeeWebJan 1, 2024 · Product Description. Phosphor- and total SLP-76 assays for monitoring T cell receptor signaling Cisbio cell-based homogeneous htrf phospho-slp-76 (Ser376) … grain cafe deliveryWebPhospho-SLP-76 (Ser376) Antibody recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. This antibody cross-reacts with a 145 kDa protein of … china lightsheer diode laser hair removalWebLymphocyte cytosolic protein (SLP-76) is required for T-cell activation and has been implicated in a number of signaling pathways. SLP76 is phosphorylated at Ser376 by HPK1, and this phosphorylation leads to a decrease in T-cell receptor signaling. o Description of the LANCE Ultra Assay china lights in wisconsinWeb(14745) Phospho-SLP-76 (Ser376) (D9D6E) Rabbit mAb Supplier Cell Signaling Technology. Host Rabbit Type Primary Clonality Recombinant (D9D6E) Recombinant Yes Conjugate Unconjugated Target Lymphocyte cytosolic protein 2 (Human) UniProt Q13094 - LCP2_HUMAN. Gene LCP2 Modification china light sneakersWebAs Phospho SLP76 (Ser396) is a readout of T cell activation, it was used to monitor the inhibitory effect of PD-L1 recombinant protein on T cell activation. This assay was performed using the two-plate assay protocol. 400 000 Jurkat cells were plated in 25 µL of complete RPMI culture medium with 10% FBS. china lights festival milwaukee