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Phospho-slp-76 ser376

WebThis assay kit contains antibodies which recognize the phospho-Ser376 epitope, and a distal epitope, on SLP-76. The protein detected by this kit corresponds to GenBank Accession U20158.1. These antibodies recognize SLP-76 of human origin. Other species should be tested on a case-by-case basis. Webimmunosuppressive environment in the presence of prostaglandin E2 (PGE-2) and are able to selectively inhibit phosphorylation of Ser376 of SLP-76. In addition, in vivo anti-tumor …

Purified anti-SLP-76 Antibody anti-SLP-76 - H76

Web15 min; green), using Phospho-SLP-76 (Ser376) (E3G9U) XP® Rabbit mAb #76384 (solid lines) or concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (dashed lines). Anti-rabbit IgG (H+L), F(ab') 2 Fragment (Alexa Fluor® 488 Conjugate) #4412 was used as a secondary antibody. Western blot analysis of extracts from Jurkat cells ... china lights hales corners wi https://kokolemonboutique.com

Cisbio 63ADK076PEH SLP-76 phospho S376 kit, 10000 …

WebPE anti-SLP76 Phospho (Ser376) Download MSDS Product data sheet Product Type: Antibodies Single Brand: Sony Clone: A18001A Application: Intracellular Flow Cytometry Isotype: Mouse IgG1, κ Reactivity: … WebThis assay kit contains antibodies which recognize the phospho-Ser376 epitope, and a distal epitope, on SLP-76. The protein detected by this kit corresponds to UniProt ID Q13094. … WebAt MetroWest Medical Center, our Speech-Language Pathology services include treatment, and management in the following areas: Dysarthria: Slurred or misarticulated speech, … grain buying jobs

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Category:Payal Mittal - Senior Scientist - Takeda LinkedIn

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Phospho-slp-76 ser376

Payal Mittal - Senior Scientist - Takeda LinkedIn

WebSLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on multiple residues, resulting in the protein being … WebMouse phospho-SLP-76 (Ser376) control lysate HTRF® This lysate is a component of the mouse phospho-SLP-76 (Ser376) kit. It may be used as a residue specific positive control for mouse SLP-76 phosphorylation. See more Size Cat. number selected : - Quantity Request for quotation Prices may differ between countries.

Phospho-slp-76 ser376

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WebSLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus … WebNo-wash kit for detection and quantitation of phospho-SLP-76 in cells using AlphaLISA SureFire technology. We are now two standalone organizations Life Sciences & …

WebSLP-76 (Phospho-Ser376) Rabbit Polyclonal Antibody Product Code AMS.BT-AP04769-100ul Skip to the end of the images gallery Skip to the beginning of the images gallery $230.00 Qty Add to Cart Request Quote for Bulk Pricing Order Support T: +1 (617) 945 5033 T: +1 (800) 987 0985 (toll free) F: +1 (617) 945 8218 Email: [email protected] WebMay 2024 - Sep 20241 year 5 months. 1250 S Collegeville Rd, Collegeville, PA 19426. • Demonstrated the in vivo efficacy of various GSK’s proprietary small molecules for their …

WebFeb 27, 2024 · Image: ELISA detection of phospho-SLP-76 (Ser376) using a FastScan™ sandwich ELISA kit from Cell Signaling Technology. Treatment efficacy is supported by Western blot analysis. Consider using automation WebJan 20, 2024 · We report here that SLP76-S376A-expressing mice exhibit normal thymocyte development and no detectable phenotypic alterations in mature T cell subsets or other lymphoid and myeloid cell lineages. Biochemical analyses revealed that mutant T cells were hypersensitive to TCR stimulation.

WebPhospho-SLP-76 (Ser376) (E3G9U) XP ® Rabbit mAb recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. Non-specific staining was observed in …

WebSLP-76 phosphorylated at Ser376 and another that recognizes an invariant epitope of SLP-76. ... Eu-Ab1 and FR-Ab2 (5 µL) for detection of phospho-SLP-76 (S376). • The plate was incubated at RT for . 18 hours. and the TR-FRET signal . was recorded at 665 and 615 nm (EnVision®; lamp excitation). grain-by-products definitonWebThe Mouse Total SLP-76 cellular assay kit is designed to monitor the expression level of SLP-76, whether phosphorylated or unphosphorylated. It is compatible with our Mouse phospho-SLP-76 (Ser376) kit, and enables the analysis of phosphorylated and total proteins from a single sample for better readouts of T-lymphocyte activation. Benefits china lights milwaukeeWebJan 1, 2024 · Product Description. Phosphor- and total SLP-76 assays for monitoring T cell receptor signaling Cisbio cell-based homogeneous htrf phospho-slp-76 (Ser376) … grain cafe deliveryWebPhospho-SLP-76 (Ser376) Antibody recognizes endogenous levels of SLP-76 protein only when phosphorylated at Ser376. This antibody cross-reacts with a 145 kDa protein of … china lightsheer diode laser hair removalWebLymphocyte cytosolic protein (SLP-76) is required for T-cell activation and has been implicated in a number of signaling pathways. SLP76 is phosphorylated at Ser376 by HPK1, and this phosphorylation leads to a decrease in T-cell receptor signaling. o Description of the LANCE Ultra Assay china lights in wisconsinWeb(14745) Phospho-SLP-76 (Ser376) (D9D6E) Rabbit mAb Supplier Cell Signaling Technology. Host Rabbit Type Primary Clonality Recombinant (D9D6E) Recombinant Yes Conjugate Unconjugated Target Lymphocyte cytosolic protein 2 (Human) UniProt Q13094 - LCP2_HUMAN. Gene LCP2 Modification china light sneakersWebAs Phospho SLP76 (Ser396) is a readout of T cell activation, it was used to monitor the inhibitory effect of PD-L1 recombinant protein on T cell activation. This assay was performed using the two-plate assay protocol. 400 000 Jurkat cells were plated in 25 µL of complete RPMI culture medium with 10% FBS. china lights festival milwaukee