WebSepsis was induced by cecal ligation and puncture in anesthetized rats. Animals were then randomly assigned to receive intravenous injection of vehicle or MRP4 inhibitor (MK571, 20 mg/kg). The pathological changes were observed by hematoxylin and eosin staining. Lung water content, lung vascular permeability and inflammatory cell count in ... WebMK 571 is a potent CysLT 1 (LTD 4) leukotriene receptor inverse agonist (EC 50 = 1.3 nM). Antagonizes LTD 4 -induced contractions of guinea pig trachea and ileum (pA 2 values are 9.4 and 10.5 respectively). Also inhibitor of multidrug resistance protein-1 (MRP1) mediated transport; in vitro augments the effects of cytotoxic agents on malignant ...
MK571 ≥99%(HPLC) Selleck LTR 阻害剤
WebMK-571(L-660711)是一种新型有效的和选择性的leukotriene D4(LTD4)受体拮抗剂,在豚鼠和人肺膜中的Ki值分别为0.22 nM和2.1 nM[1]。MK-571也是多药耐药蛋白1(MRP1)的特异性抑制剂[2]。 Leukotriene D4 (LTD4)是一种由嗜碱性粒细胞产生的白三烯。LTD4诱导平滑肌的收缩,增加血管通透性。 WebCurrent Weather. 5:11 AM. 47° F. RealFeel® 48°. Air Quality Excellent. Wind NE 2 mph. Wind Gusts 5 mph. Clear More Details. task bar moved to side in outlook
MK-571 . sodium salt (CAS: 115103-85-0 115104-28-4 (free base))
WebApr 6, 2024 · cysLT1レセプターアンタゴニスト。LTD4のヒトおよびモルモットの肺細胞膜への結合を阻害するが,LTC4は阻害しない。M.W.:515.1,純度:≥95%,化学 … Web「MK-571 (sodium salt)」。富士フイルム和光純薬株式会社は、試験研究用試薬・抗体の製造販売および各種受託サービスを行っています。 Web特異的なMRP抑制薬MK571は、脳の組織とフラ午前2時(1つのmicroM)と一緒の潜伏の間の甲殻類ウミザリガニ属ガンマルス(ロブスター) … the buck ashton on mersey