Web1 day ago · When brains of 7-month-old MPS IIIC mice were analysed by ex-vivo Diffusion Basis Spectrum Imaging to assess microarchitectural changes in the corpus callosum, we found compelling signs of demyelination (26% increase in radial diffusivity) and tissue loss (76% increase in hindered diffusivity). WebCentral demyelination of the corpus callosum (Marchiafava-Bignami disease) with report of a second case in Great Britain Brain. 1961 Jun;84:212-30.doi: …
Central nervous system Cryptococcoma mimicking demyelinating disease: a ...
WebNov 1, 2003 · Summary: Marchiafava-Bignami is a rare toxic disease seen mostly in chronic alcoholics that results in progressive demyelination and necrosis of the corpus callosum. The process may extend laterally into the neighboring white matter and occasionally as far as the subcortical regions. We present the MR imaging findings in two patients who … WebThe corpus callosum consists of densely bundled white matter tracts connecting the two cerebral hemispheres, with a compact structure that largely blocks interstitial edema and … themasharani.practice nhs.net
Severe Central Nervous System Demyelination in …
WebJun 9, 2024 · In this disorder, your immune system attacks the myelin sheath or the cells that produce and maintain it. This attack causes inflammation and injury to the nerve sheath and ultimately to the nerve fibers that it surrounds. The process can result in multiple areas of scarring (sclerosis). WebThinning of the corpus callosum can be primary or secondary, and generalized or focal. Primary thinning is caused by abnormal or failed myelination related to the hypomyelinating leukoencephalopathies, metabolic disorders affecting white matter, and microcephaly. WebAug 12, 2024 · Brain MRI revealed a rim-enhanced mass within the corpus callosum body. Central nervous system demyelinating disease was suspected. Empirical corticosteroid treatment led to some improvement, but his condition deteriorated 2 months later. Brain MRI revealed punctate new foci. Cryptococcus neoformans was detected in cerebrospinal fluid. themashavo