WebCorrection to: Bladder Cancer Progression Is Suppressed Through the Heart and Neural Crest Derivatives Expressed 2‑Antisense RNA 1/microRNA‑93‑5p/Defective in Cullin Neddylation 1 Domain Containing 3 Axis. ... South Branch of Fujian Provincial Hospital, Fuzhou, 350001, China. [email protected]. PMID: 37052864 WebApr 22, 2024 · Developing nanocarrier systems with sufficient drug loading ability and efficient drug release behavior in cells is a powerful strategy to maximize therapeutic efficacies and minimize side effects of administered drugs. However, the two aspects are usually contradictory in a single nanocarrier. Herein, polyphenol-DNA nanocomplex with …
Synthesis of branched antisense oligonucleotides having …
WebOct 23, 2024 · Constructing Branched Antisense and siRNA Co-assembled Nanoplatform for Combined Gene Silencing and Tumor Therapy. A research team led by Prof. … WebLocked nucleic acid. Chemical structure of an LNA monomer an additional bridge bonds the 2' oxygen and the 4' carbon of the pentose. A locked nucleic acid ( LNA ), also known as bridged nucleic acid (BNA), [1] and often referred to as inaccessible RNA, is a modified RNA nucleotide in which the ribose moiety is modified with an extra bridge ... c3 snowbike intake
Treatment of MCF-7 breast cancer cells employing mono- and
WebOct 15, 2024 · A nucleic acid nanoplatform‐based co‐delivery system containing a pair of functionalized branched antisenses and siRNA with 3′ overhangs was constructed … WebThis work introduces a facile and universal strategy to construct a DNA nanostructure-based codelivery system containing a linear tumor therapeutic gene (p53) and a chemotherapeutic drug (doxorubicin, DOX) for combined therapy of multidrug resistant tumor (MCF-7R). 161 Progress and problems with the use of viral vectors for gene therapy WebAug 7, 2008 · Previous studies have demonstrated that monospecific antisense oligonucleotides (oligos) directed against mRNA encoding proteins associated with tumor growth, death, and survival are efficacious against breast and prostate tumors. Targeted proteins, associated with different signal transduction pathways, have included … c3 teknoloji istanbul